17 - These Blind Mice: When Bench Doesn't Meet Bedside

Monday, October 20, 2025

8:00 AM - 9:00 AM US ET

Location: B213-B214

CME Credits: Maximum of 1 hours of AMA PRA Category 1 Credit™
MOC Credits: Maximum of 1 hours of MOC Credit
CNE Credits: Maximum of 1 hours of ANCC Credit
ACPE Credits: ACPE 1 knowledge-based contact hours of pharmacy CE
ACPE Number: JA0007082-9999-24-002-L01-P
PACE Credits: Maximum of 1 of PACE contact hours
CE Broker: Maximum of 1 CE broker credit hours

Moderator(s)

Luther Bartelt, MD

Associate Professor, Infectious Diseases
University of North Carolina School of Medicine
Chapel Hill, NC, United States
Mahalia Desruisseaux, MD (she/her/hers)

Associate Professor
Yale School of Medicine
New Haven, CT, United States

Faculty(s)

Gauri Rao, PharmD, MS

Associate Professor
Clinical Pharmacy Department
USC Alfred E. Mann School of Pharmaceiti
Rancho Palos Verdes, CA, United States
Ying Taur, MD, MPH (he/him/his)

Associate Attending
Memorial Sloan Kettering Cancer Center
New York, NY, United States

Disclosure(s):

Luther A. Bartelt, MD: No financial relationships to disclose.

Mahalia S. Desruisseaux, MD: No financial relationships to disclose.

Gauri G. Rao, PharmD, MS: No financial relationships to disclose.

Ying Taur, MD, MPH: Seres Therapeutics: Advisor/Consultant

Learning Objectives:

At the conclusion of this session, participants will be able to:

describe examples of 'lessons learned' regarding when bench findings didn't translate to clinical outcomes;
relate heterogeneity in clinical outcomes to defined biological parameters that may drive between-host variability;
explain a basic framework for appraising discordant findings between experimental laboratory outcomes and clinical outcomes.

Presentations:

8:00 AM - 8:30 AM US ET

Optimizing Dosing Strategies: Insights From Systems Pharmacology and Experimental Models
Speaker: Gauri G. Rao, PharmD, MS – USC Alfred E. Mann School of Pharmaceiti
8:30 AM - 9:00 AM US ET

Unmeasured Variables: Microbiome-Mediated Effects of Treatment Outcomes
Speaker: Ying Taur, MD, MPH (he/him/his) – Memorial Sloan Kettering Cancer Center