72 - Late Breaking Trial Results For Viral and Bacterial Infections

Moderator(s)

• 

  Yohei Doi, MD, PHD (he/him/his)

  Professor of Medicine
  Division of Infectious Diseases
  University of Pittsburgh
  Toyoake, Aichi, Japan
• 

  Michael Calderwood, MD, MPH (he/him/his)

  Chief Quality Officer
  Section of Infectious Disease and International Health
  Dartmouth Hitchcock Medical Center
  Hanover, NH, United States

Presentations:

• 1:45 PM - 1:57 PM US ET

  Efficacy and Immunogenicity of WRSs2, a Live Attenuated Shigella sonnei Vaccine Candidate, to Protect Against Shigellosis After Challenge with a Wild-type S. sonnei strain 53G.
  

  Presenting Author: Robert W. Frenck, Jr., MD – Cincinnati Children's Hospital

  Co-Author: Nadine Rouphael, MD – Emory University School of Medicine

  Co-Author: Shahida Baqar, PhD – NIH

  Co-Author: Michelle Dickey, APRN – Cincinnati Children's Hospital

  Co-Author: Veronica Smith, MSN, NP-C – Emory University School of Medicine, The Hope Clinic of the Emory Vaccine Center

  Co-Author: Jill El-Khorazaty, PhD – Emmes

  Co-Author: Monica McNeil, MS – Cincinnati Children's Hospital

  Co-Author: Christina M. Quigley, PhD – Cincinnati Children's Hospital Medical Center

  Co-Author: Erin Scherer, PhD – Emory University School of Medicine

  Co-Author: Jamie Fraser, MPH – Emmes

  Co-Author: Tena Pham, RN – Cincinnati Children's Hospital

  Co-Author: Carson Caldwell, RN – Cincinnati Children's Hospital

  Co-Author: Lori Newman, MD – NIH

  Co-Author: Sarah Bechnak, MSN, NP-BC – Emory University

  Co-Author: Shoshana Barnoy, PhD – Walter Reed Army Institute of Research

  Co-Author: Lakshmi Chandrasekaran, PhD – Walter Reed Army Institute of Research

  Co-Author: Chad Porter, PhD – Naval Medical Research Center

  Co-Author: Susan Heard, BS – Emmes

  Co-Author: Akamol Suvarnapunya, PhD – Walter Reed Army Institute of Research

  Co-Author: Krista Cato, RN, MHA – NIH

  Co-Author: Malabi Venkatesan, PhD – Walter Reed Army Institue of Research
• 1:57 PM - 2:09 PM US ET

  The First Proof-of-Concept Clinical Trial of an HIV-1 Allosteric Integrase Inhibitor, Pirmitegravir (STP0404)
  

  Co-Author: Moti Ramgopal, MD, FACP, FIDSA (he/him/his) – Midway Immunology and Research Center

  Co-Author: Paul Benson, DO – Be Well Medical Center

  Co-Author: John C. Williamson, PharmD (he/him/his) – Wake Forest School of Medicine

  Co-Author: Mezgebe Berhe, MD, MPH – North Texas Infectious Diseases Consultants

  Co-Author: Peter Ruane, MD – Ruane Clinical Research, Los Angeles, CA, USA

  Co-Author: Beata Casanas, MD – University of South Florida

  Co-Author: Edwin DeJesus, MD – Orlando Immunology Center, University of Central Florida College of Medicine

  Co-Author: Christopher Lucasti, MD – South Jersey Infectious Disease

  Presenting Author: Xue Meng, MS – ST Pharm Co., Ltd.

  Co-Author: Uk-Il Kim, MS – ST Pharm Co., Ltd.

  Co-Author: Song Hyun Kim, MS – ST Pharm Co., Ltd.

  Co-Author: Moo Je Sung, PhD – ST Pharm Co., Ltd.
• 2:09 PM - 2:21 PM US ET

  Oral Tebipenem Pivoxil Hydrobromide versus Intravenous Imipenem-Cilastatin in Patients with Complicated Urinary Tract Infections or Acute Pyelonephritis: Efficacy and Safety Results from the Phase 3 PIVOT-PO study
  

  Presenting Author: David K. Hong, MD – Spero Therapeutics Inc., Cambridge, MA, USA

  Co-Author: Sibel Ascioglu, MD – GSK, London, UK

  Co-Author: Nivedita Bhatt, PhD – Spero Therapeutics

  Co-Author: Ian A. Critchley, PhD – Spero Therapeutics Inc., Cambridge, MA, USA

  Co-Author: Masha Gaber, ALM – Spero Therapeutics Inc., Cambridge, MA, USA

  Co-Author: Leanne B. Gasink, MD – Spero Therapeutics Inc., Cambridge, MA, USA

  Co-Author: Kamal A. Hamed, MD – Spero Therapeutics Inc., Cambridge, MA, USA

  Co-Author: Aubri Hutchins, BA – Spero Therapeutics Inc., Cambridge, MA, USA

  Co-Author: Aoibhinn McDonnell, DVM – GSK, Stevenage, UK

  Co-Author: Tal Otiker, MSc – GSK, London, UK

  Co-Author: Yasmin Sánchez-Pearson, PhD – GSK, London, UK

  Co-Author: Amanda J. Sheets, PhD – GSK, Collegeville, PA, USA

  Co-Author: Dan Sotolongo, MD – Links Clinical Trials, LLC, Miami, FL, USA

  Co-Author: Mike Sprys, MSc – GSK, Philadelphia, PA, USA

  Co-Author: Didem Torumkuney, PhD – GSK

  Co-Author: Kamil Wrzosek, MD – Czerniakowski Hospital, Warsaw, Poland

  Co-Author: Amanda Peppercorn, MD – GlaxoSmithKline
• 2:21 PM - 2:33 PM US ET

  Generic Lenacapavir HIV Pre-Exposure Prophylaxis could be Produced for $25 Per Person Per Year
  

  Co-Author: Cassandra Fairhead, MBBS – Royal Free Hospital, London

  Co-Author: Joseph Fortunak, PhD – Department of Chemistry, Howard University, Washington, D.C., USA 20905

  Co-Author: Jevon Layne, BS – Johns Hopkins School of Medicine, 1650 Orleans St, RM162A, Baltimore, MD USA 21287

  Co-Author: Madison Johnson, BS – Department of Chemistry, Howard University, Washington, D.C., USA 20905

  Co-Author: Samyah Smalley, BS – Department of Chemistry, Howard University, Washington, D.C., USA 20905

  Co-Author: Andrew Lutterodt, BS – QIAGEN, Frederick MD USA 20874

  Co-Author: David Roberts, BS – – Department of Chemistry, Howard University, Washington, D.C., USA 20905

  Co-Author: Endalkachew Tadesse, BEd – Department of Chemistry, Howard University, Washington, D.C., USA 20905

  Co-Author: Jasmine Lu, BS – Lu Global Consulting, South Brunswick NJ, USA 08824

  Co-Author: Eloan Pinheiro, PhD – Consultant, ARV development and manufacturing, Rio de Janeiro, Brazil 22753-806

  Co-Author: Messay Wolde-Mariam, MSc – Pharmaceutical Industry Development Sector, Armauer Hansen Research Institute, Addis Ababa, Ethiopia

  Presenting Author: Andrew Hill, PhD – University of Liverpool

  Co-Author: Toby Pepperrel, MBBS – Biological and Environmental Sciences, University of Stirling, Stirling, Scotland
• 2:33 PM - 2:45 PM US ET

  An Open-Label Phase 1 Clinical Trial Demonstrating Improved Immune Responses to Norovirus Strains GI.1 and GII.4 from a Second Generation Oral Bivalent Vaccine Candidate
  

  Presenting Author: Nicholas J. Bennett, MBBChir, PhD – Vaxart Inc

  Co-Author: Becca A. Flitter, PhD, MPH – Vaxart Inc

  Co-Author: Colin A. Lester, n/a – Vaxart, Inc.

  Co-Author: Nick P. D'Amato, MSc – Vaxart Inc.

  Co-Author: Maria D. Apkarian, N/A, BA – Vaxart Inc.

  Co-Author: Sean N. Tucker, PhD – Vaxart

  Co-Author: James F. Cummings, MD – VAXART
• 2:45 PM - 2:57 PM US ET

  Remdesivir for Post-Exposure Prophylaxis of Marburg Virus Disease: A Cohort Study Assessing Safety, Clinical, and Immunologic Outcomes.
  

  Presenting Author: Tsion Firew, MD,MPH,FACEP (she/her/hers) – Africa, Health Sciences University, Kigali, Rwanda King Faisal Hospital Rwanda, Kigali, Rwanda and New York University, New York, USA

  Co-Author: Anna Dobbins, MPH – Rwanda Ministry of Health

  Co-Author: Espoir Hakizimana, MD,Msc – Africa, Health Sciences University, Kigali, Rwanda King Faisal Hospital Rwanda, Kigali, Rwanda

  Co-Author: Appolinaire Manirafasha, MD,MMED – King Faisal Hospital Rwanda, Kigali, Rwanda

  Co-Author: Vanessa Nadine Ineza, RN Critical Care and Trauma – King Faisal Hospital Rwanda, Kigali, Rwanda

  Co-Author: Zerihun Abebe, MD – King Faisal Hospital Rwanda, Kigali, Rwanda

  Co-Author: Kara L. Neil, EdP – Africa, Health Sciences University, Kigali, Rwanda and King Faisal Hospital Rwanda, Kigali, Rwanda

  Co-Author: John Baptist Nkuranga, MD,MMED – King Faisal Hospital Rwanda, Kigali, Rwanda

  Co-Author: Janvier Ndayambaje, MPH – Africa, Health Sciences University, Kigali, Rwanda King Faisal Hospital Rwanda, Kigali, Rwanda

  Co-Author: Rafiki Gatera Michel, Msc – King Faisal Hospital Rwanda, Kigali, Rwanda

  Co-Author: Claude Mambo Muvunyi, PHD – RWANDA BIOMEDICAL CENTER

  Co-Author: Edson Rwagasore, MD,Msc – Rwanda Biomedical Center, Kigali, Rwanda

  Co-Author: Jean Claude S. Ngabonziza, PHD – Rwanda Biomedical Center, Kigali, Rwanda

  Co-Author: Menelas Nkeshimana, MD,MMED – Ministry of Health, Kigali, Rwanda

  Co-Author: Yvan Butera, PHD – Ministry of Health Rwanda

  Co-Author: Sabin Nzanzimana, PHD – Ministry of Health Rwanda

  Co-Author: Ryan Westergaard, MD, PhD, MPH – University of Wisconsin School of Medicine and Public Health