37 - Novel Insights on Safety, Interactions and Drug Resistance

Rapid Fire Moderator(s)

• 

  Jorge Salazar, MD (he/him/his)

  Assistant Professor
  University of California, San Francisco
  San Francisco, CA, United States

Presentations:

• 12:15 PM - 12:20 PM US ET

  Modeling Confirms Islatravir 0.25 mg Administered Daily Has No Adverse Effect on Total Lymphocyte or CD4+ T-cell Counts in People Living with HIV
  

  Rapid Fire Presenter: Brian M. Maas, PharmD (he/him/his) – Merck & Co., Inc.

  Co-Author: Bill Poland, PhD – Certara

  Co-Author: Michelle M. Pham, PhD (she/her/hers) – Merck & Co., Inc.

  Co-Author: Martin Johnson, PhD – Allucent

  Co-Author: Irene Bae, PharmD – Certara

  Co-Author: Seth H. Robey, PhD – Merck & Co., Inc.

  Co-Author: Bhargava Kandala, PhD – Merck & Co., Inc.

  Co-Author: Xiaowei Zang, PhD – Merck & Co., Inc.

  Co-Author: Stephanie O. Klopfer, PhD – Merck & Co., Inc.

  Co-Author: Michelle C. Fox, MD – Merck & Co., Inc.

  Co-Author: Ryan C. Vargo, PhD – Merck & Co., Inc.
• 12:20 PM - 12:25 PM US ET

  No Clinically Significant Drug-Drug Interactions Between Lenacapavir and Hormonal Contraceptives in PURPOSE 1
  

  Rapid Fire Presenter: Disebo Potloane, MB, ChB, Dip. HIV Man (she/her/hers) – Centre for the AIDS Programme of Research in South Africa (CAPRISA)

  Co-Author: Cheryl E. Louw, MB, ChB – Madibeng Centre for Research

  Co-Author: Godfrey Kigozi, MB, ChB – Africa Medical and Behavioral Sciences Organization

  Co-Author: Moelo Malahleha, MB, ChB – Synergy Biomed Research Institute

  Co-Author: William Brumskine, MB, ChB, Dip. HIV Man (SA) – The Aurum Institute

  Co-Author: Amy Ward, MBBCh, Dip. HIV Man – Vuka Research Clinic, University of Cape Town

  Co-Author: Dhayendre Moodley, PhD – Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal

  Co-Author: Alexander Kintu, MB, ChB, ScD – Gilead Sciences, Inc.

  Co-Author: Marjorie Z. Imperial, PhD – Gilead Sciences, Inc.

  Co-Author: Priyanka Arora, PhD – Gilead Sciences, Inc.

  Co-Author: Renu Singh, PhD, MS – Gilead Sciences, Inc.

  Co-Author: Lillian B. Brown, MD, PhD – Gilead Sciences, Inc.

  Co-Author: Christoph C. Carter, MD, PhD – Gilead Sciences, Inc.

  Co-Author: Flavia Matovu Kiweewa, MB, ChB, MSc, PhD – Makerere University—Johns Hopkins University Research Collaboration
• 12:25 PM - 12:30 PM US ET

  No Clinically Significant Drug–Drug Interactions with Co-administration of Feminizing or Masculinizing Hormone Therapy and Twice-yearly Lenacapavir PrEP in Gender-Diverse Persons
  

  Rapid Fire Presenter: Jill Blumenthal, MD MAS (she/her/hers) – University of California San Diego

  Co-Author: Maribel Acevedo-Quinones, MD – Centro Ararat

  Co-Author: Nittaya Phanuphak, MD, PhD – Institute of HIV Research and Innovation – Pribta Tangerine Clinic

  Co-Author: Juan Carlos Hinojosa, MD – Asociación Civil Selva Amazónica

  Co-Author: Javier R. Lama, MD, MPH – Asociación Civil Impacta Salud y Educacion

  Co-Author: Michelle Cespedes, MD, MS – Icahn School of Medicine at Mount Sinai; Mount Sinai Health System

  Co-Author: Nkosiphile Ndlovu, MBChB, Dip. HIV Man – Wits RHI, Faculty of Health Sciences, School of Public Health, University of the Witwatersrand

  Co-Author: Carlos Brites, MD, PhD – Complexo Hospitalar Universitário Professor Edgard Santos

  Co-Author: Sarah B. Puryear, MD, MPH – Gilead Sciences, Inc.

  Co-Author: Lillian B. Brown, MD, PhD – Gilead Sciences, Inc.

  Co-Author: Christoph C. Carter, MD, PhD – Gilead Sciences, Inc.

  Co-Author: Priyanka Arora, PhD – Gilead Sciences, Inc.

  Co-Author: Marjorie Z. Imperial, PhD – Gilead Sciences, Inc.

  Co-Author: Kim Etchevers, MS – Gilead Sciences, Inc.

  Co-Author: Renu Singh, PhD, MS – Gilead Sciences, Inc.

  Co-Author: Pamela Wong, MPH – Gilead Sciences, Inc.

  Co-Author: Olivia T. Van Gerwen, MD, MPH – University of Alabama at Birmingham
• 12:30 PM - 12:35 PM US ET

  Pooled safety and tolerability of twice-yearly lenacapavir with teropavimab and zinlirvimab for HIV-1 treatment
  

  Co-Author: Kimberly Workowski, MD – Department of Medicine, Emory University, Atlanta, GA, USA

  Co-Author: Peter Ruane, MD – Ruane Clinical Research, Los Angeles, CA, USA

  Co-Author: Anthony Mills, MD – Men's Health Foundation, Los Angeles, CA, USA

  Rapid Fire Presenter: Mehri S. McKellar, MD (she/her/hers) – Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC, USA

  Co-Author: Olayemi O. Osiyemi, MD – Triple O Research Institute PA, West Palm Beach, Florida, USA

  Co-Author: Linda Gorgos, MD, MSc, FIDSA – AXCES Research Group, Santa Fe, NM, USA

  Co-Author: Gordon E. Crofoot, MD – The Crofoot Research Center, Houston, TX, USA

  Co-Author: Moti Ramgopal, MD, FACP, FIDSA (he/him/his) – Midway Immunology and Research Center

  Co-Author: Cynthia C. Brinson, MD – Central Texas Clinical Research, Austin, TX, USA

  Co-Author: Kwad Mponponsuo, MD, MSc – Gilead Sciences, Inc., Foster City, CA, USA

  Co-Author: Sean E. Collins, MD, MS – Gilead Sciences, Inc., Foster City, CA, USA

  Co-Author: Hui Liu, PhD – Gilead Sciences, Inc., Foster City, CA, USA

  Co-Author: Nan Zhang, PhD – Gilead Sciences, Inc., Foster City, CA, USA

  Co-Author: Keith Flower, MD – Gilead Sciences, Inc., Foster City, CA, USA

  Co-Author: Tina Chakrabarti, MD – Gilead Sciences, Inc., Foster City, CA, USA

  Co-Author: Onyema Ogbuagu, MA, FACP, FIDSA – Yale School of Medicine
• 12:35 PM - 12:40 PM US ET

  HIV drug resistance-associated mutations within molecular clusters of rapid HIV transmission, 2018–2023
  

  Rapid Fire Presenter: Katherine C. McNabb, PhD, DNP – Centers for Disease Control and Prevention

  Co-Author: Neeraja Saduvala, MS – SeKON

  Co-Author: Kathryn Curran, PhD, MPH – Centers for Disease Control and Prevention

  Co-Author: Richard Teran, PhD, MPH – Centers for Disease Control and Prevention

  Co-Author: Anne Marie France, PhD, MPH – Centers for Disease Control and Prevention

  Co-Author: Walid Heneine, PhD – Centers for Disease Control and Prevention

  Co-Author: Rachael Billock, PhD – Centers for Disease Control and Prevention

  Co-Author: Joel Wertheim, PhD – University of California, San Diego

  Co-Author: Angela L. Hernandez, MD, DBA, MPH – Centers for Disease Control and Prevention

  Co-Author: Alexandra Oster, MD – Centers for Disease Control and Prevention