105 - Synergy and Strategy: Combinations and Dosing to Defeat VRE

Tuesday, October 21, 2025

8:00 AM - 9:00 AM US ET

Location: B314

CME Credits: Maximum of 1 hours of AMA PRA Category 1 Credit™
MOC Credits: Maximum of 1 hours of MOC Credit
CNE Credits: Maximum of 1 hours of ANCC Credit
ACPE Credits: ACPE 1 knowledge-based contact hours of pharmacy CE
ACPE Number: JA0007082-9999-24-002-L01-P
PACE Credits: Maximum of 1 of PACE contact hours
CE Broker: Maximum of 1 CE broker credit hours

Moderator(s)

Amit Pai, PharmD

Professor and Chair
University of Michigan, MI, United States
Cecilia Tran, PharmD

Research Scientist
Houston Methodist Hospital
Houston, TX, United States

Faculty(s)

Ashlan Kunz Coyne, B.S., PharmD, MPH

Assistant Professor
University of Kentucky College of Pharmacy
Lexington, KY, United States
YuChung Chuang, MD PhD (he/him/his)

Clinical Professor
National Taiwan University Hospital

Disclosure(s):

Amit Pai, PharmD: No financial relationships to disclose.

Cecilia Tran, PharmD: No financial relationships to disclose.

Ashlan J. Kunz Coyne, B.S., PharmD, MPH: No financial relationships to disclose.

YuChung Chuang, MD PhD: No financial relationships to disclose.

Learning Objectives:

At the conclusion of this session, participants will be able to:

evaluate the clinical applications, dosing strategies, and therapeutic outcomes of high-dose daptomycin in the treatment of vancomycin-resistant Enterococcus (VRE) infections;
discuss novel approaches to combating VRE, including the use of antimicrobial combinations and phage-cocktail therapies, to enhance efficacy and overcome resistance;
apply the latest research and clinical insights on synergistic therapies to optimize treatment regimens and improve patient outcomes in VRE infections.

Presentations:

8:00 AM - 8:30 AM US ET

Clinical Applications of High Dose Daptomycin
Speaker: YuChung Chuang, MD PhD (he/him/his) – National Taiwan University Hospital
8:30 AM - 9:00 AM US ET

Emerging Strategies for Antimicrobial Combinations and Phage Cocktails
Speaker: Ashlan J. Kunz Coyne, B.S., PharmD, MPH – University of Kentucky College of Pharmacy