117 - Recent Advances in Understanding Respiratory Microbial Communities: From Association to Translation

Tuesday, October 21, 2025

10:30 AM - 11:45 AM US ET

Location: Thomas B. Murphy Ballroom 4

CME Credits: Maximum of 1.25 hours of AMA PRA Category 1 Credit™
MOC Credits: Maximum of 1.25 hours of MOC Credit
CNE Credits: Maximum of 1.25 hours of ANCC Credit
ACPE Credits: ACPE 1.25 knowledge-based contact hours of pharmacy CE
ACPE Number: JA0007082-9999-24-002-L01-P
PACE Credits: Maximum of 1 of PACE contact hours
CE Broker: Maximum of 1 CE broker credit hours

Moderator(s)

Mahalia Desruisseaux, MD (she/her/hers)

Associate Professor
Yale School of Medicine
New Haven, CT, United States
Matthew Kelly, MD, MPH (he/him/his)

Professor of Pediatrics
University of Arkansas for Medical Sciences
Little Rock, AR, United States

Faculty(s)

CL

Chaz Langelier, MD PhD

University of California San Francisco
San Francisco, California, United States
Katherine Lemon, MD, PhD (she/her/hers)

Associated Professor of Molecular Virology & Microbiology and of Pediatrics
Baylor College of Medicine
Matthew Kelly, MD, MPH (he/him/his)

Professor of Pediatrics
University of Arkansas for Medical Sciences
Little Rock, AR, United States

Disclosure(s):

Mahalia S. Desruisseaux, MD: No financial relationships to disclose.

Matthew S. Kelly, MD, MPH: Merck and Company, Inc.: Advisor/Consultant, Grant/Research Support

Katherine P. Lemon, MD, PhD: OraSure Technologies, Inc.: Advisor/Consultant

Learning Objectives:

At the conclusion of this session, participants will be able to:

explain how disruptions in the microbiome can impact antimicrobial resistance;
describe how microbes interact with human nasal epithelia using biomimetic organoids;
discuss how host-microbe metagenomics can inform the diagnosis of lower respiratory tract infections.

Presentations:

10:30 AM - 10:55 AM US ET

The Upper Respiratory Microbiome: Shaping Health and Disease
Speaker: Matthew S. Kelly, MD, MPH (he/him/his) – University of Arkansas for Medical Sciences
10:55 AM - 11:20 AM US ET

Human Respiratory Organoids for Elucidating Microbe-Host Interaction
Speaker: Katherine P. Lemon, MD, PhD (she/her/hers) – Baylor College of Medicine
11:20 AM - 11:45 AM US ET

Diagnosing Pneumonia With Next-Generation Sequencing
Speaker: Charles Langelier, MD PhD – University of California San Francisco