241 - Advances in Managing Antimicrobial Toxicities

Wednesday, October 22, 2025

1:45 PM - 3:00 PM US ET

Location: Thomas B. Murphy Ballroom 1

CME Credits: Maximum of 1.25 hours of AMA PRA Category 1 Credit™
MOC Credits: Maximum of 1.25 hours of MOC Credit
CNE Credits: Maximum of 1.25 hours of ANCC Credit
ACPE Credits: ACPE 1.25 knowledge-based contact hours of pharmacy CE
ACPE Number: JA0007082-9999-24-002-L01-P
PACE Credits: Maximum of 1 of PACE contact hours
CE Broker: Maximum of 1 CE broker credit hours

Moderator(s)

Amit Pai, PharmD

Professor and Chair
University of Michigan, MI, United States
Marc Scheetz, PharmD, MSc

Professor and Associate Dean of Research
Pharmacy and Pharmacology
Midwestern University
Downers Grove, IL, United States

Faculty(s)

Yukihiro Hamada, Pharmacy PhD (he/him/his)

Director/professor
Pharmacy
Department of Pharmacy, Kochi Medical School Hospital
NANKOKU, Kochi, Japan
Michael Neely, MD

Pediatric Infectious Diseases
Children’s Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA
Los Angeles, CA, United States
Michael Veve, PharmD, MPH

Clinical Associate Professor
Eugene Applebaum College of Pharmacy and Health Sciences
Detroit, MI, United States

Disclosure(s):

Amit Pai, PharmD: No financial relationships to disclose.

Marc H. Scheetz, PharmD, MSc: Ark Biopharmaceutical: Advisor/Consultant; iFAST: Advisor/Consultant; Meitheal pharmaceuticals: Advisor/Consultant; SKK: Advisor/Consultant

Yukihiro Hamada, Pharmacy PhD: No financial relationships to disclose.

Michael N. Neely, MD: No financial relationships to disclose.

Michael P. Veve, PharmD, MPH: Biomeriux: Advisor/Consultant; Blue Cross Blue Shield of Michigan: Grant/Research Support; Merck Sharp & Dohme Corp: Advisor/Consultant, Grant/Research Support; Nestle: Grant/Research Support

Learning Objectives:

At the conclusion of this session, participants will be able to:

describe the mechanisms, clinical presentation, and management strategies for thrombocytopenia caused by antibiotic therapies;
analyze the risk factors, diagnostic approaches, and preventive measures for hepatotoxicity associated with antifungal medications;
discuss the clinical implications of neutropenia induced by antibiotics, including monitoring practices and therapeutic interventions to reduce patient risks.

Presentations:

1:45 PM - 2:10 PM US ET

Antibiotic-Induced Thrombocytopenia
Speaker: Michael N. Neely, MD – Children’s Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA
2:10 PM - 2:35 PM US ET

Antifungal-Induced Hepatotoxicity
Speaker: Yukihiro Hamada, Pharmacy PhD (he/him/his) – Department of Pharmacy, Kochi Medical School Hospital
2:35 PM - 3:00 PM US ET

Antibiotic-Induced Neutropenia: Quantifying Risk and Mitigation Strategies
Speaker: Michael P. Veve, PharmD, MPH – Eugene Applebaum College of Pharmacy and Health Sciences